Human RAD51(RAD51 Homolog) ELISA Kit

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human RAD51 Homolog (RAD51) in tissue homogenates, cell lysates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human RAD51 Homolog (RAD51) in tissue homogenates, cell lysates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human RAD51 Homolog (RAD51) in tissue homogenates, cell lysates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human RAD51 Homolog (RAD51) in tissue homogenates, cell lysates and other biological fluids.

Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human RAD51 Homolog (RAD51) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Description: Recombinant Human RAD51 Homolog expressed in: E.coli

Description: A sandwich ELISA kit for detection of RAD51 Homolog from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Description: A Rabbit polyclonal antibody against Human RAD51 Homolog (RAD51)

Description: A Rabbit polyclonal antibody against Human RAD51 Homolog (RAD51). This antibody is labeled with APC.

Description: A Rabbit polyclonal antibody against Human RAD51 Homolog (RAD51). This antibody is labeled with Biotin.

Description: A Rabbit polyclonal antibody against Human RAD51 Homolog (RAD51). This antibody is labeled with Cy3.

Description: A Rabbit polyclonal antibody against Human RAD51 Homolog (RAD51). This antibody is labeled with FITC.

Description: A Rabbit polyclonal antibody against Human RAD51 Homolog (RAD51). This antibody is labeled with HRP.

Description: A Rabbit polyclonal antibody against Human RAD51 Homolog (RAD51). This antibody is labeled with PE.

Description: A Rabbit polyclonal antibody against Human RAD51 Homolog (RAD51). This antibody is labeled with APC-Cy7.

Description: Quantitative sandwich ELISA for measuring Human DNA repair protein RAD51 homolog 1 (RAD51) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Human DNA repair protein RAD51 homolog 1 (RAD51) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Human DNA repair protein RAD51 homolog 1 (RAD51) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Rabbit polyclonal RAD51 antibody

Description: A polyclonal antibody against RAD51. Recognizes RAD51 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/20000

Description: RAD51 Antibody detects endogenous levels of total RAD51.

Description: A polyclonal antibody against RAD51. Recognizes RAD51 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100

Description: A polyclonal antibody against RAD51. Recognizes RAD51 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:5000, IHC:1:25-1:100

Description: A polyclonal antibody against RAD51. Recognizes RAD51 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/10000

Description: A polyclonal antibody against RAD51. Recognizes RAD51 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100

Description: Rabbit polyclonal RAD51 antibody

Description: Purified Rabbit polyclonal RAD51 antibody

Description: A polyclonal antibody against RAD51. Recognizes RAD51 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB

Description: A polyclonal antibody against RAD51. Recognizes RAD51 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF, IP; Recommended dilution: WB:1:2000-1:5000, IHC:1:20-1:200, IF:1:50-1:200, IP:1:200-1:2000

Description: Mouse polyclonal to Rad51

Description: Rabbit polyclonal to Rad51

Description: Mouse polyclonal to Rad51

Description: The Rad51 Protein (Human) is available in Europe and for worldwide shipping via Gentaur.

Description: The Rad51 Protein (Human) is available in Europe and for worldwide shipping via Gentaur.

Description: Description of target: The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.115 ng/mL

Description: Description of target: Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange (PubMed:26681308). Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.9 Publications <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More…</a></p> Manual assertion based on experiment iniRef.5"Identification of a novel human Rad51 variant that promotes DNA strand exchange."_x005F_x005F_x000D_Park J.Y., Yoo H.W., Kim B.R., Park R., Choi S.Y., Kim Y._x005F_x005F_x000D_Nucleic Acids Res. 36:3226-3234(2008) [PubMed] [Europe PMC] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3), FUNCTION OF ISOFORMS 1 AND 3, TISSUE SPECIFICITY (ISOFORMS 1 AND 3), SUBCELLULAR LOCATION (ISOFORMS 1 AND 3), MUTAGENESIS (ISOFORM 3).Ref.18"Homologous DNA pairing by human recombination factors Rad51 and Rad54."_x005F_x005F_x000D_Sigurdsson S., Van Komen S., Petukhova G., Sung P._x005F_x005F_x000D_J. Biol. Chem. 277:42790-42794(2002) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION.Ref.27"Physical interaction of RECQ5 helicase with RAD51 facilitates its anti-recombinase activity."_x005F_x005F_x000D_Schwendener S., Raynard S., Paliwal S., Cheng A., Kanagaraj R., Shevelev I., Stark J.M., Sung P., Janscak P._x005F_x005F_x000D_J. Biol. Chem. 285:15739-15745(2010) [PubMed] [Europe PMC] [Abstract]Cited for: INTERACTION WITH RECQL5, FUNCTION.Ref.28"Discovery of a novel function for human Rad51: maintenance of the mitochondrial genome."_x005F_x005F_x000D_Sage J.M., Gildemeister O.S., Knight K.L._x005F_x005F_x000D_J. Biol. Chem. 285:18984-18990(2010) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, SUBCELLULAR LOCATION, INDUCTION.Ref.30"RecQL5 promotes genome stabilization through two parallel mechanisms--interacting with RNA polymerase II and acting as a helicase."_x005F_x005F_x000D_Islam M.N., Fox D. III, Guo R., Enomoto T., Wang W._x005F_x005F_x000D_Mol. Cell. Biol. 30:2460-2472(2010) [PubMed] [Europe PMC] [Abstract]Cited for: INTERACTION WITH RECQL5, FUNCTION.Ref.42"FIGNL1-containing protein complex is required for efficient homologous recombination repair."_x005F_x005F_x000D_Yuan J., Chen J._x005F_x005F_x000D_Proc. Natl. Acad. Sci. U.S.A. 110:10640-10645(2013) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, INTERACTION WITH FIGNL1; RAD51AP1 AND SWI5, SUBCELLULAR LOCATION, IDENTIFICATION BY MASS SPECTROMETRY.Ref.43"Scaffolding protein SPIDR/KIAA0146 connects the Bloom syndrome helicase with homologous recombination repair."_x005F_x005F_x000D_Wan L., Han J., Liu T., Dong S., Xie F., Chen H., Huang J._x005F_x005F_x000D_Proc. Natl. Acad. Sci. U.S.A. 110:10646-10651(2013) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, IDENTIFICATION IN A COMPLEX WITH BLM AND SPIDR, INTERACTION WITH SPIDR, SUBCELLULAR LOCATION.Ref.46"Insights into DNA recombination from the structure of a RAD51-BRCA2 complex."_x005F_x005F_x000D_Pellegrini L., Yu D.S., Lo T., Anand S., Lee M., Blundell T.L., Venkitaraman A.R._x005F_x005F_x000D_Nature 420:287-293(2002) [PubMed] [Europe PMC] [Abstract]Cited for: X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS) OF 97-339 IN COMPLEX WITH BRCA2, FUNCTION, SUBUNIT, MUTAGENESIS OF PHE-86 AND ALA-89, SUBCELLULAR LOCATION, INTERACTION WITH BRCA2.Ref.48"A novel Fanconi anaemia subtype associated with a dominant-negative mutation in RAD51."_x005F_x005F_x000D_Ameziane N., May P., Haitjema A., van de Vrugt H.J., van Rossum-Fikkert S.E., Ristic D., Williams G.J., Balk J., Rockx D., Li H., Rooimans M.A., Oostra A.B., Velleuer E., Dietrich R., Bleijerveld O.B., Maarten Altelaar A.F., Meijers-Heijboer H., Joenje H. , Glusman G., Roach J., Hood L., Galas D., Wyman C., Balling R., den Dunnen J., de Winter J.P., Kanaar R., Gelinas R., Dorsman J.C._x005F_x005F_x000D_Nat. Commun. 6:8829-8829(2015) [PubMed] [Europe PMC] [Abstract]Cited for: VARIANT THR-293, CHARACTERIZATION OF VARIANT THR-293, FUNCTION, SUBCELLULAR LOCATION. ;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 0.118 ng/mL

Description: Rabbit polyclonal RAD51 antibody (Thr309)

Description: Purified Rabbit polyclonal RAD51 antibody (Tyr315)

Description: A polyclonal antibody for detection of Rad51 from Human, Mouse. This Rad51 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Rad51 around the non-phosphorylation site of Y315

Description: A polyclonal antibody for detection of Rad51 from Human, Mouse. This Rad51 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Rad51 around the non-phosphorylation site of Y315

Description: A polyclonal antibody for detection of Rad51 from Human, Mouse. This Rad51 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Rad51 around the non-phosphorylation site of Y315